Juvenile ankylosing spondylitis

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Juvenile ankylosing spondylitis.

Fifteen patients with juvenile ankylosing spondylitis were reviewed. Eight presented with extraspinal arthritis. Certain clinical features were of value early in the disease in distinguishing these patients from those with juvenile rheumatoid arthritis: male sex, remittent oligoarthritis, late onset in childhood, relative sparing of hands and wrists, infrequent cervical spine involvement, and n...

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Urolithiasis in ankylosing spondylitis: Correlation with Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)

Background: Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. Methods: One hundred-sixty three AS patients were included in a cross-s...

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Differences between juvenile-onset ankylosing spondylitis and adult-onset ankylosing spondylitis.

BACKGROUND Ankylosing spondylitis (AS) is a chronic inflammatory disease, which involves the spine, peripheral joints and entheses. Juvenile-onset ankylosing spondylitis (JAS) affects children under the age of 16 years. JAS has been noted to present as clinical courses different from those of adult-onset ankylosing spondylitis (AAS). Therefore, the purpose of the present study was to compare th...

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TNF-alpha antagonists for treatment of juvenile ankylosing spondylitis

Background Juvenile onset sondylarthropathy is a term that refers to a group of human leucocyte antigen (HLA) -B27 associated inflammatory disorders affecting children under the age of 16 years. The increased expression of tumor necrosis factor alpha (TNF-alpha) in synovial tissue of patients with juvenile onset and adults with active ankylosing spondylitis suggests a significant pathogenic rol...

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Complement-Mediated Muscle Involvement in Juvenile Ankylosing Spondylitis

An 18-year-old Brazilian man had developed ankylosing spondylitis with positive HLAB27 at 13. He had spine and sacro-iliac joint involvement and aortitis with valve regurgitation. He was referred for myalgia and marked increased creatine kinase. Neurological examination did not disclose muscle wasting or weakness. Muscle biopsy demonstrated slight fibre size variability and normal membrane prot...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1971

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780140505